Scientific Journal of Depression & Anxiety

Scientific Journal of Depression & Anxiety (SJDA) is an Open Access peer reviewed, online publishing journal which aims to publish scholarly and quality papers in the significant areas of current Depression and Anxiety. 

Depression and Anxiety is a branch of medicine dealing with disorders of the brain as well as parts of the center nervous system. Depression and anxiety disorders are different, but people with depression regularly experience symptoms similar to those of an anxiety disorder, such as nervousness, irritability, and problems sleeping and concentrating. But, each disorder has its own causes and its own emotional and behavioral symptoms.

Aims and Scope:

The scope of the journal highlights the advanced topics in depression is a condition in which a person feels discouraged, sad, hopeless, unmotivated, or disinterested in life in general. When these feelings last for a short period of time, it may be a case of "the blues", Major depression, Persistent depressive disorder and bipolar disorder.

Source: https://bit.ly/2JNj4AW

Effects of Treatment of Varicose Veins on the Occurrence of Complications and to Improve the Quality of Life: Pilot Study?

According to statistics, the disorder of venous circulation of the lower extremities is one of the most common diseases in the world. Although treatment of Varicose Veins the lower extremities (VV) advanced with the use of non-invasive-endovenous procedures, the prognosis in the short term is not satisfactory. The aim of this paper was to examine the results of treatment of VV on the occurrence of complications and to improve the Quality of Life (QoL) 1 year after the Operative (OP) treatment or Endovenous Laser Ablation (EVLA).

Method: Patients with VV that were operated with the classical surgical method were OP group (n-36) and who are treated EVLA were EVLA group (n-36). We examined patients clinically after 1 year of treatment, while their QoL examined with the Venous Clinical Severity Score (VCSS) questionnaire in which clinical features were estimated by 9 characteristics clinical weight of : 0-absence, 1-easy, 2-moderate, 3-diffi cult.

Source: https://bit.ly/2M2AonB

Hematological and Pathological Studies of Bacteria Associated with Mobile Phones from Handlers of Diverse Lifestyles in the Rural Community.

Mobile phone has been source of microorganisms that cause diseases of public health concerns. In a study, one-fifth of cellular phones examined were found to harbor pathogenic bacteria indicating that these devices may serve as vehicles of transmission. Swab samples were collected aseptically from the phones of different handlers like motor bike riders, food vendors, meat sellers and nursing mothers.

Bacteria isolation and identification were carried out using pour plating technique with distinctive morphological and biochemical characteristics. The pathogenicity of the bacterial isolates was investigated through oral inoculation into albino rats. Eighty-eight (88) bacteria were isolated and selected based on their resistance to antibiotics for pathological study. Loss in weight was observed in some albino rat. Along with reduction in the packed cell volume, hemoglobin but raised white blood cell. Animal inoculated with Bacillus cereus showed meningitis like symptom after the first week of inoculation. Also, there were short and stunted villi; low crystal depth with necrotic debris in the lumen. It has been observed that cell phones may harbor pathogenic bacteria and can subsequently plays role as fomite in the disease transmission. Therefore, the need to educate community phone handlers in the rural area becomes imperative.

                                                 

1.1 Animal without Bacteria Inoculation (Control) 

   

1.2 Animal Showing Abnormal Neck Twisting after challenged with Bacillus cereus two weeks after inoculation

Why is it important to publish the research paper in good publication?

Good journals are not necessarily the same - but in many cases a correlation exists.

Basically there are two reasons why people publish their research work:

1. To make everyone in the field aware of the research they have lead. Their research serves as a forum for the exchange of ideas among scientists, young researchers, students and readers from all over the world. 

2. To gain respect of their peers and improve their CV. So that when they apply for the next job, they can objectively prove that they are indeed doing noble research. 

You might think that just making your research publicly accessible on the internet should be sufficient for point 1, but it’s not true. Most researchers/ scientists/ professors can’t keep pathway of the thousands of articles published every year in their field. They tend to follow some journals (by subscribing to emails of the table of contents of every issue) and attend a few conferences to be aware of current growth in the field. If you publish your work at an unknown site that is accessible to very few people, it is very likely that it will be lost in the enormous volume of research being produced.

Good journals also help your research through a strict peer-review. In my experience, peer reviews of most of my papers has been very useful. In most cases, the peer review helps you to improve the quality of the paper. And once you’ve had enough articles peer-reviewed, you tend to understand the common errors that should be avoided and in general become a better communicator of ideas.

Blood Cancer: Is it Curable?

Blood is produces in Bone marrow, the place where most of the cancers occur or start. Blood Cancers like( Leukemia, myeloma, lymphoma affects the production and functioning of blood cells as a result of this blood cells lack their function in fighting off injections and prevention of serious bleeding.

For many patients with blood cancer the best and the only way to cure it is the stem cell transplant which is a part of their treatment. In this stem cell transplant a new immune system is developed by the donor stem cell which has the potential to view cancer cells as foreign and lead to their suppression.

                           

The patients who need transplant do not have matching donor in their family, according to surveys there are 70 percent of patience with this instance. Hence they have to rely on international cooperative registries or “Be the Match Registry” through National Marrow Donor Program. Yet 6 out of 10 patients cannot find a genetic in the impressive 11 million donor registries. For diverse ancestry the probability is even low.

Those who register mail back a swab of cheek cells that are used for tissue typing and matching. On an average a total of 500 members will be selected to donate their stem cells in the span of two days. There are two ways of donation the Peripheral blood stem cell donation is non-surgical, this process of collection of stem cells take a six year period via peripheral blood. The other is surgical process which takes about 1-2 hours and it is performed under anesthesia where marrow cells are collected with a syringe from pelvic bone.

By Ellen Barrett

16-11-2018

“Stress = Death”: Can stress cause you?

“Stress = Death”: Can stress cause you?

There are many ways that chronic stress can cause you death. Cortisol which is often referred as stress hormone includes in that. Elevated Cortisol levels interact and interfere with learning, memorizing, lowering the immunity system and lessens its functioning, there are lot many more factors like decrease in bone density and increasescholesterol and level of lying on the bed of heart diseases rate increases drastically.

Chronic Stress is hazardous and causes heart related diseases which leads to early death and can also cause cancer and other health related issues in the early ages.

The most stressed out people will have a premature death with higher risk and with higher rate. According to some studies 1293 men annually have premature deaths with chronic stress.

What is Chronic Stress?

Chronic Stress is a response to emotional&psychological pressures suffered and prolonged for a large period of time in which the individual have little or no control on the situation by which he goes through.

• Depression or general unhappiness.
• Anxiety and agitation.
• Moodiness, irritability, or anger.
• Feeling overwhelmed.
• Loneliness and isolation.
• Other mental or emotional health problems.

The above mentioned are the symptoms of Chronic stress, to overcome stress chronic stress one should know its symptoms, and then find a remedy to overcome the stress factor.

Chronic Stress in Females

In females the death ratio is low compared to men. But chronic stress has been linked with many severe problems in female reproduction both in human and non- human animals in many studies. But contrast, to this very less researches have been focused on relationship between chronic stress and sexual functioning. Many women daily experience a hectic lives, in which they are frequently exposed to small,chronic stressors. By regular accumulation of these small stressors can potentially contribute its part related to sexual functioning.

Finally high level of chronic stress in female will relate to lower level of genetic sexual arousal and high level of chronic stress in males might lead to death.

Ø    Distracting is the only significant predictor when controlling for other variables.

By Anicia Clark

10-09-2018

Probiotics is this the reason of worsening Cryptosporidiosis in mice.

Being administered a probiotic, researchers have found that infection with intestinal parasite Cryptosporidium parvum is worsened in mice.

Cryptosporidiosis is one of the main cause of diarrhea in most of the developing and under developing countries on an estimate of over 48000 people were killed in 2016. Doctors and researchers have not yet found any drug that can treat the infection and any vaccine that can prevent it.

Compared to control mice, those that were given the probiotic had altered gut micro flora and more parasites in their feces, and their intestinal micro flora were different from those of the control mice.

Researchers and doctors assumed that healthy microbiome could prevent or reduce the severity of the infection, but contrary to their expectational assumptions, they came to notice that consumption of commercially available probiotic actually increased the severity of the infection.

                            

Antibiotics, which often disturb or even use up and empty all the normal intestinal micro flora, thus can render individuals more vulnerable to infection precisely related to intestine. On the other hand, researches posited that a healthy balance of microflora can prevent or reduce severity of cryptosporidiosis in a mouse model.

“Mitigating the diseases severity might be adequate to prevent diarrhea, or lessen the duration, and empower the immunes system so to naturally control the infection”

Although the outcome of the study was quite contrary to their hypothesis, the fact that cryptosporidium growth can be affected by diet has meant Widmer and colleagues now think that it may still be possible to design probiotics that will mitigate the infection.

Widmer says that the aim now is to find a find a mechanistic link between microflora and cryptosporidium proliferation and ultimately design a simple nutritional supplement that helps the body fight the infection.

“Identifying specific mechanisms that amend pathogen virulence in response to diet may enhance the development of simple pre- or probiotics capable of modifying the composition of the microbiota to lower the severity of cryptosporidiosis.”

Story Source: https://goo.gl/nemd3P

By Anicia Clark

05-09-2018